Cytoplan Vitamin B12 Hydroxocobalamin is at a high potency of 1mg (1,000µg) per sublingual tablet.
Sublingual means beneath the tongue and these tablets will dissolve in the mouth allowing oral absorption.
Hydroxocobalamin is an inactive form of vitamin B12. It is converted into the active methylcobalamin in the body. For some people this form may be indicated rather than the active methylcobalamin (see also our Vitamin B12 Methylcobalamin/Adenosylcobalamin)
Hydroxocobalamin B12 has high affinity to plasma proteins and so may be retained in the blood stream for a much longer period of time, compared to cyanocobalamin.
Hydroxocobalamin B12 may be indicated:
- to start supplementation of B12 if one has both a folate and a vitamin B12 deficiency
- as a scavenger of nitric oxide, an essential muscle regulator that also acts as a free radical. Too much nitric oxide can contribute to oxidative stress
- vegan and vegetarian diets can be low in B12
- other people at risk of low B12 include those with digestive conditions that lead to malabsorption; low stomach acid (e.g. due to long-term antacid medication, proton pump inhibitors, H2 blockers, ageing or zinc deficiency); surgery where nitrous oxide has been used as an anaesthetic; and other prescription medications which impair B12 absorption (e.g. metformin, colchicine, neomycin and others)
Vitamin B12 contributes to normal:
- energy-yielding metabolism
- functioning of the nervous system
- homocysteine metabolism
- psychological function
- red blood cell formation
- immune system function
Vitamin B12 contributes to the reduction of tiredness and fatigue.
Vitamin B12 has a role in the process of cell division